People

Xiaochuan Pan, PhD

Research of Professor Pan’s lab centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. Dr. Pan and his lab conduct research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT), supported by grants from federal funding agencies such as NIH and DOD, from state funding agencies, from foundations, and from industry. In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed programs that translate theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance. Dr. Pan's lab has established continuous, close clinical and industrial collaboration. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE.

Collision-avoiding imaging trajectories for linac mounted cone-beam CT.
Davis AM, Pearson EA, Pan X, Pelizzari CA, Al-Hallaq H. Collision-avoiding imaging trajectories for linac mounted cone-beam CT. J Xray Sci Technol. 2019; 27(1):1-16.
PMID: 30400125

Estimating the spectrum in computed tomography via Kullback-Leibler divergence constrained optimization.
Ha W, Sidky EY, Barber RF, Schmidt TG, Pan X. Estimating the spectrum in computed tomography via Kullback-Leibler divergence constrained optimization. Med Phys. 2019 Jan; 46(1):81-92.
PMID: 30370544

The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission.
Xie KX, Xu LT, Zhai YY, Wang ZC, Chen M, Pan XH, Cao SH, Li YQ. The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission. Talanta. 2019 Apr 01; 195:752-756.
PMID: 30625612

Optimization-based image reconstruction from sparsely sampled data in electron paramagnetic resonance imaging.
Qiao Z, Zhang Z, Pan X, Epel B, Redler G, Xia D, Halpern H. Optimization-based image reconstruction from sparsely sampled data in electron paramagnetic resonance imaging. J Magn Reson. 2018 09; 294:24-34.
PMID: 30005191

Algorithm-enabled partial-angular-scan configurations for dual-energy CT.
Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Algorithm-enabled partial-angular-scan configurations for dual-energy CT. Med Phys. 2018 May; 45(5):1857-1870.
PMID: 29516523

Reduction of Angularly-Varying-Data Truncation in C-Arm CBCT Imaging.
Xia D, Chang YB, Manak J, Siddiqui AH, Zhang Z, Chen B, Sidky EY, Pan X. Reduction of Angularly-Varying-Data Truncation in C-Arm CBCT Imaging. Sens Imaging. 2018 Dec; 19.
PMID: 30319317

Image reconstruction and scan configurations enabled by optimization-based algorithms in multispectral CT.
Chen B, Zhang Z, Sidky EY, Xia D, Pan X. Image reconstruction and scan configurations enabled by optimization-based algorithms in multispectral CT. Phys Med Biol. 2017 Nov 02; 62(22):8763-8793.
PMID: 29094680

Investigating simulation-based metrics for characterizing linear iterative reconstruction in digital breast tomosynthesis.
Rose SD, Sanchez AA, Sidky EY, Pan X. Investigating simulation-based metrics for characterizing linear iterative reconstruction in digital breast tomosynthesis. Med Phys. 2017 Sep; 44(9):e279-e296.
PMID: 28901614

Optimization-based image reconstruction with artifact reduction in C-arm CBCT.
Xia D, Langan DA, Solomon SB, Zhang Z, Chen B, Lai H, Sidky EY, Pan X. Optimization-based image reconstruction with artifact reduction in C-arm CBCT. Phys Med Biol. 2016 10 21; 61(20):7300-7333.
PMID: 27694700

Investigation of optimization-based reconstruction with an image-total-variation constraint in PET.
Zhang Z, Ye J, Chen B, Perkins AE, Rose S, Sidky EY, Kao CM, Xia D, Tung CH, Pan X. Investigation of optimization-based reconstruction with an image-total-variation constraint in PET. Phys Med Biol. 2016 08 21; 61(16):6055-84.
PMID: 27452653

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