Greg Karczmar - Publications

Selected peer-reviewed publications (in chronological order; from a total of 71 published or in press):

1. Al-Hallaq HA, Zamora M, Fish BL, Farrell A, Moulder JE, Karczmar GS. MRI measurements correctly predict the relative effects of tumor oxygenating agents on hypoxic fraction in rodent BA1112 tumors. Int J Radiat Oncol Biol Phys 2000, 47 (2) 481-8

2. Evelhoch JL, Gillies RJ, Karczmar GS, Koutcher JA, Maxwell RJ, Nalcioglu O, Raghunand N, Ronen SM, Ross BD, Swartz HM. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia 2000, 2 (1-2) 152-65

3. Karczmar GS, Fan X, Al-Hallaq HA, Zamora M, River JN, Rinker-Schaeffer C, Zaucha M, Tarlo K, Kellar K. Uptake of a superparamagnetic contrast agent imaged by MR with high spectral and spatial resolution. Magn Reson Med 2000, 43 (5) 633-9

4. Fan X, River JN, Zamora M, Tarlo K, Kellar K, Rinker-Schaeffer C, Karczmar GS. Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI. Magn Reson Med 2001, 45 (6) 1046-55

5. Al-Hallaq HA, Fan X, Zamora M, River JN, Moulder JE, Karczmar GS. Spectrally inhomogeneous BOLD contrast changes detected in rodent tumors with high spectral and spatial resolution MRI. NMR Biomed 2002, 15 (1) 28-36

6. Du W, Karczmar GS, Pan X. Effects of constant frequency noise in magnetic resonance imaging with nonuniform k-space sampling. Med Phys 2002, 29 (8) 1832-8

7. Du W, Du YP, Bick U, Fan X, MacEneaney PM, Zamora MA, Medved M, Karczmar GS. Breast MR imaging with high spectral and spatial resolutions: preliminary experience. Radiology 2002, 224 (2) 577-85

8. Fan X, River JN, Zamora M, Al-Hallaq HA, Karczmar GS. Effect of carbogen on tumor oxygenation: combined fluorine-19 and proton MRI measurements. Int J Radiat Oncol Biol Phys 2002, 54 (4) 1202-9

9. Fan X, Du W, MacEneaney P, Zamora M, Karczmar G. Structure of the water resonance in small voxels in rat brain detected with high spectral and spatial resolution MRI. J Magn Reson Imaging 2002, 16 (5) 547-52

10. Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. J Magn Reson Imaging 2002, 16 (4) 430-50

11. Karczmar GS, Du W, Medved M, Bick U, MacEneaney P, Du YP, Fan X, Zamora M, Lipton M. Spectrally inhomogeneous effects of contrast agents in breast lesion detected by high spectral and spatial resolution MRI. Acad Radiol 2002, 9 Suppl 2 S352-4

12. Karczmar GS, Fan X, Al-Hallaq H, River JN, Tarlo K, Kellar KE, Zamora M, Rinker-Schaeffer C, Lipton MJ. Functional and anatomic imaging of tumor vasculature: high-resolution MR spectroscopic imaging combined with a superparamagnetic contrast agent. Acad Radiol 2002, 9 Suppl 1 S115-8

13. Williams BB, al Hallaq H, Chandramouli GV, Bart ED, Rivers JN, Lewis M, Galtsev VE, Karczmar GS, Halpern HJ. Imaging spin probe distribution in the tumor of a living mouse with 250 MHz EPR: correlation with BOLD MRI. Magn Reson Med 2002, 47 (4) 634-8

14. Du W, Du YP, Fan X, Zamora MA, Karczmar GS. Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic imaging of water and fat resonances. Magn Reson Med 2003, 49 (6) 1113-20

15. Al-Hallaq HA, Zamora MA, Fish BL, Halpern HJ, Moulder JE, Karczmar GS. Using high spectral and spatial resolution bold MRI to choose the optimal oxygenating treatment for individual cancer patients. Adv Exp Med Biol 2003, 530 433-40

16. Elas M, Williams BB, Parasca A, Mailer C, Pelizzari CA, Lewis MA, River JN, Karczmar GS, Barth ED, Halpern HJ. Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level-dependent (BOLD) MRI. Magn Reson Med 2003, 49 (4) 682-91

17. Medved M, Du W, Zamora MA, Fan X, Olopade OI, MacEneaney PM, Newstead G, Karczmar GS. The effect of varying spectral resolution on the quality of high spectral and spatial resolution magnetic resonance images of the breast. J Magn Reson Imaging 2003, 18 (4) 442-8

18. Fan X, Medved M, River JN, Zamora M, Corot C, Robert P, Bourrinet P, Lipton M, Culp RM, Karczmar GS. New model for analysis of dynamic contrast-enhanced MRI data distinguishes metastatic from nonmetastatic transplanted rodent prostate tumors. Magn Reson Med 2004, 51 (3) 487-94

19. M Medved, G Newstead, X Fan, W Du, Y Du, P MacEneaney, RM Culp, F Kelcz, O Olopade, M Zamora, GS Karczmar. Fourier Components of Inhomogeneously Broadened Water Resonances in Breast: A New Source of MRI Contrast. Magnetic Resonance in Medicine 52: 193-196, 2004.

20. AC Peterson, S Swiger, WM Stadler, M Medved, GS Karczmar, TF Gajewski: Phase II study of the Flk-1 Tyrosine Kinase Inhibitor SU5416 in advanced melanoma. Clinical Cancer Research 10: 4048 - 4053, 2004.

21. C Yang, GS Karczmar, M Medved, W Stadler. Estimating the Arterial Input Function Using Two Reference Tissues in Dynamic Contrast-Enhanced MRI Studies. 1. Fundamental Concepts and Simulations. Magnetic Resonance in Medicine 52: 1110-1117, 2004

22. M Medved, GS Karczmar, J Dignam, TF Gajewski, H Kindler, E Vokes, P MacEneany, W Stadler. Semiquantitative analysis of dynamic contrast enhanced MRI in cancer patients: Variability and changes in tumor tissue over time. Journal of Magnetic Resonance Imaging 20: 122-128, 2004.

23. W Du, X Fan, S Foxley, M Zamora, J River, R Culp, GS Karczmar. Comparison of high resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice. NMR in Biomedicine 18: 285 – 292, 2005.

24. W Du, GS Karczmar, S Uftring, YP Du. Anatomic and functional brain imaging using high resolution echo-planar spectroscopic imaging at 1.5 Tesla. NMR in Biomedicine 18: 235 – 241, 2005.

25. M Medved, G Newstead, H Abe, M Zamora, O Olopade, GS Karczmar. High spectral and spatial resolution MR imaging of breast lesions: preliminary clinical experience. American Journal of Roentgenology, American Journal of Roentgenology, 186: 30 – 37, 2006.

26. X Fan, JN River, AS Muresan, C Popescu, M Zamora, RM Culp, GS Karczmar. MRI of perfluorocarbon emulsion kinetics in rodent mammary tumors. Physics in Medicine and Biology 51: 211-220, 2006.

27. X Fan, M Medved, S Foxley, JN River, M Zamora, GS Karczmar, C Corot, P Robert, P Bourrinet. Multi-slice dynamic contrast-enhanced MRI using P760 distinguishes between metastatic and non-metastatic rodent prostate tumors. MAGMA, 19: 15 -21, 2006.

Full CV