My lab develops algorithms and algorithm-enabled imaging systems at scales from nanometers (x-ray microscopy) to meters (human computed tomography). Themes that span all scales and modalities include dose reduction, material identification, and orientation imaging.
University of Chicago
Chicago, IL
Ph.D. - Medical Physics
2000
Cambridge University
Cambridge, UK
- Philosophy of physics
1995
Harvard University
Cambridge, MA
A.B. - Physics
1994
Efficient spatio-angular reconstruction enables high-fidelity mapping of six-dimensional structures and dynamics with polarized fluorescence microscopy.
Efficient spatio-angular reconstruction enables high-fidelity mapping of six-dimensional structures and dynamics with polarized fluorescence microscopy. Nat Commun. 2026 Aug 17; 17(1).
PMID: 42744799
Label-free 3D virtual histology of human formalin-fixed paraffin-embedded (FFPE) prostate needle biopsies with propagation-based phase-contrast micro-CT (PBCT).
Label-free 3D virtual histology of human formalin-fixed paraffin-embedded (FFPE) prostate needle biopsies with propagation-based phase-contrast micro-CT (PBCT). bioRxiv. 2026 Jun 07.
PMID: 42292910
Racial differences in texture analysis features of the choriocapillaris.
Racial differences in texture analysis features of the choriocapillaris. Can J Ophthalmol. 2026 Aug; 61(4):929-935.
PMID: 41679722
A Bayesian multivariate spatial point pattern model: application to oral microbiome FISH image data.
A Bayesian multivariate spatial point pattern model: application to oral microbiome FISH image data. Biostatistics. 2026 01 20; 27(1).
PMID: 42613133
Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy.
Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy. bioRxiv. 2025 Sep 25.
PMID: 41480145
The origin of vertebrate teeth and evolution of sensory exoskeletons.
The origin of vertebrate teeth and evolution of sensory exoskeletons. Nature. 2025 06; 642(8066):119-124.
PMID: 40399678
Volumetric imaging of the 3D orientation of cellular structures with a polarized fluorescence light-sheet microscope.
Volumetric imaging of the 3D orientation of cellular structures with a polarized fluorescence light-sheet microscope. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2406679122.
PMID: 39982748
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy.
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy. Nat Commun. 2025 01 02; 16(1):313.
PMID: 39747824
Photon Counting: Detectors and Applications.
Photon Counting: Detectors and Applications. J Med Imaging (Bellingham). 2024 Dec; 11(Suppl 1):S12801.
PMID: 39742118
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy.
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy. bioRxiv. 2024 Jul 15.
PMID: 37986950
Distinguished investigator
Academy for Radiology and Biomedical Imaging Research
2018
Fellow
Marine Biological Laboratory
2016
Young Investigator Medical Imaging Scientist Award
IEEE
2005
Lionel deJersey Harvard Scholarship to Cambridge University
Harvard University
1994