Bill C. O'Brien-Penney

Associate Professor of Radiology
Clinical Physicist for Nuclear Medicine

Phone: 773.702.0910
Fax: 773.702.2530


Undergraduate: BS, Electrical Engineering, Worcester Polytechnic Institute (WPI),
Worcester, MA, 1973
Graduate: MS, BioMedical Engineering, WPI, Worcester, MA 1976
Doctorate: PhD, BioMedical Engineering, WPI, Worcester, MA, 1979
Certification: American Board of Radiology in Medical Nuclear Physics, 1995


  • Eta Kappa Nu (Electrical Engineering Honor Society)
  • Teacher of the Year, 2004, 2010, Graduate Program in Medical Physics, Radiology Dept., University of Chicago
  • “Making the Difference”, 2005 Staff Appreciation Award, Radiology Dept., University of Chicago
  • Vice Chair -University and University Hospitals Combined Human Use of Radioisotopes and Radioactive Drug Research Advisory Committee (RADRAC)
  • Chair - Clinical Regulatory Compliance Subcommittee of the RADRAC
  • Secretary - Computer & Instrumentation Council, Society of Nuclear Medicine, 2005-07
  • Reviewer for Medical Physics and IEEE Medical Imaging Conference

Research Interests

Scatter correction in SPECT and PET, quantifying therapy response with PET, and using PET to reflect hepatic glucose-6-phosphatase activity